Tenofovir linked with acute kidney injury in HIV-infected patients

Acute kidney injury (AKI) associated with tenofovir disoproxil fumarate (TDF) was prevalent among HIV-infected patients and demonstrated a high morbidity rate in a new center-based study. More than half of patients with TDF-associated AKI did not recover baseline kidney function during follow-up, and about one-third of the patients required dialysis, according to new research.